Polyclonal Ready-to-Use

Alpha1-Antichymotrypsin

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human. Shows no cross-reactivity with horse, sheep, swine, goat, cow, dog, cat, chicken, rat, mouse, mink, kangaroo or Guinea pig. Positive Control: Tonsil Specificity: This antibody recognizes macrophages and monocytes in human colon, tonsil and skin. RUO Datasheet European Customer Datasheet

Alpha1-Antitrypsin

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human and Swine. Stains weakly with horse, dog and mink, and shows no cross-reactivity with sheep, goat, cow, cat, chicken, rat, mouse, kangaroo or Guinea pig. Positive Control: Tonsil Specificity: This antibody recognizes macrophages in human colon and tonsil. RUO Datasheet European Customer Datasheet

Alpha1-Fetoprotein (AFP)

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: This antibody reacts with alpha-1-fetoprotein. A positive staining in the hepatocytes of fetal tissue was observed. This antibody does not react with other cell or tissue types. RUO Datasheet European Customer Datasheet

Bcl-6

	Species: Rabbit Clone: Polyclonal Species Reactivity: Human, Mouse, and Rat. Specificity: This antibody reacts with bcl-6 of mouse, rat and human cell origin. Relatively little is known regarding the molecular pathogenesis of diffuse large-cell lymphoma (DLCL). DLCL accounts for approximately 40% of all non-Hodgkin lymphomas. Chromosomal translocations involving reciprocal recombination between band 3q27 and several other chromsomal sites are involved in 8 to 12% of non-Hodgkin’s lymphomas; a breakpoint cluster region at 3q27 has been identified and designated bcl-6. More recently this gene has been shown to encode a protein of 706 aminio acids with predicted molecular weight of 79 kD. This bcl-6 protein has homology with zinc finger-transcription factors and was found to be rearranged in 13 of 39 DLCL samples. RUO Datasheet European Customer Datasheet

Calcitonin

	Species: Rabbit Clone: Polyclonal Specificity: This antibody reacts with the mu-chains of human IgM. Nonspecific antibodies have been removed by solid-phase absorption. RUO Datasheet European Customer Datasheet

Cathepsin D

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Positive Control: Macrophages in breast carcinoma. Specificity: This antibody reacts with the zymogen as well as the activated form of cathepsin D. It stains fibroblasts and macrophages strongly but stains myoepithelial cells of breast weakly. In addition, this antibody stains the sweat ducts and glands in the skin, islet cells and granules of pancreatic acini. RUO Datasheet European Customer Datasheet

CD3, T-Cell

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Positive Control: Tonsil Specificity: This antibody reacts with intracytoplasmic portion of the CD3 antigen on the T cells. It stains T cells in cortex as well as medulla of the thymus and lymphoid tissues. This antibody also labels T cell neoplasm, malignant histiocytes and in Hodgkin’s disease. RUO Datasheet European Customer Datasheet

c-erbB-2 Oncoprotein

	Species: Rabbit Polyclonal Clone: Polyclonal MW: 190 kD Species Reactivity: Human Specificity: This antibody reacts with the c-erbB-2 oncoprotein, a 190 kD protein. The proto-oncogene for c-erbB-2 is located on the human chromosome 17, band 21. RUO Datasheet European Customer Datasheet

Chromogranin A

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: This antibody reacts with human chromogranin A in the neuroendocrine cells and neural tissues. It does not recognize the epitopes located on the N-terminal half of the chromogranin A molecule. RUO Datasheet European Customer Datasheet

Factor VIII Related Antigen

	Species: Rabbit Polyclonal Clone: Polyclonal MW: 270 kD Species Reactivity: Human Positive Control: Blood vessels in skin or intestine Specificity: Recognizes a multimeric glycoprotein of 270kDa, identified as factor VIII related antigen or von Willebrand factor. This protein has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. Von Willebrand factor is synthesized by endothelial cells and stored in the Weibel-Palade granules. It mediates platelet adhesion to injured vessel walls and serves as a carrier and stabilizer for coagulation factor VIII. ScyTek’s antibody reacts specifically with the endothelial cells of normal, reactive, and neoplastic blood and lymphatic vessels and shows a finely granular cytoplasmic staining. It also reacts with endocardium, platelets and megakaryocytes. Von Willebrand factor is one of the most useful markers to identify endothelial (or megakaryocytic) lineage of neoplasms. However, because not all endothelial cells synthesize (or store) this molecule, about 30% of tumors of vascular origin fail to stain for factor VIII related antigen, regardless of whether they are benign or malignant. RUO Datasheet European Customer Datasheet

HbcAg - Hepatitis B Virus Core

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: This antibody reacts in the nuclei of the liver cells of the Hepatitis type B virus infected patients. However, occasional staining may also be seen in the perinuclear cytoplasm of the infected cells. RUO Datasheet European Customer Datasheet

IgA

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: This antibody reacts with alpha-chains of human Ig A. This antibody has been absorbed to a very high level of specificity. RUO Datasheet European Customer Datasheet

IgG

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: This antibody reacts with gamma-chains of human IgA. Nonspecific antibodies have been removed by solid-phase absorption. RUO Datasheet European Customer Datasheet

IgM

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: This antibody reacts with the m chains of human IgM. Nonspecific antibodies have been removed by solid-phase absorption.< RUO Datasheet European Customer Datasheet

Kappa Light Chain

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: This antibody reacts with free as well as bound kappa light chains. Contaminating antibodies have been removed by solid phase absorption. RUO Datasheet European Customer Datasheet

Ki-67 Antigen

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: This antibody reacts with a nuclear antigen present in proliferating human cells. This antibody cross-reacts with a range of mammalian species. RUO Datasheet European Customer Datasheet

Lambda Light Chain

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: This antibody reacts with free as well as bound lambda light chains. Contaminating antibodies have been removed by solid phase absorption. RUO Datasheet European Customer Datasheet

Lysozyme

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human, Baboon, Monkey, Pig, Cat, Dog, Mouse and Rat. Positive Control: Tonsil, colon or skin Specificity: This polyclonal antibody recognizes a protein, identified as lysozyme, also known as muramidase. This antibody was adsorbed with human plasma and urine proteins to remove the cross-reacting antibodies. Lysozymes synthesized predominantly in reactive histiocytes rather than in resting, unstimulated phagocytes. It labels myeloid cells, histiocytes, granulocytes, macrophages, and monocytes. This antibody is helpful in the identification of myeloid or monocytic nature of acute leukemia. RUO Datasheet European Customer Datasheet

Myoglobin

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: This antibody reacts with human myoglobin. The antibody stains strongly with the skeletal and cardiac muscles. No non-specific staining with other tissues has been observed. RUO Datasheet European Customer Datasheet

Papillomavirus (Pan-HPV)

	Species: Rabbit Polyclonal Clone: Polyclonal Species Reactivity: Human Specificity: Bovine papillomavirus type 2. Reacts with all human papillomavirus types (genus specific). RUO Datasheet European Customer Datasheet