c-erbB-2 Oncoprotein; Clone SP3
Mol. Weight: 185kD
Species Reactivity: Human. Others not tested.
Positive Control: Breast carcinoma.
Cellular Localization: Cell membrane.
Specificity: c-erbB-2 is a receptor tyrosine of the c-erbB family. It is closely related in structure to the epidermal growth factor receptor. C-erbB-2 oncoprotein is detectable in a proportion of breast and other adenocarcinomas, as well as transitional cell carcinomas.