TRAcP (Tartrate-Resistant Acid Phosphatase); Clone ACP5/1070 (Concentrate)
Immunogen: Recombinant human ACP5 protein
Isotype: IgG2b, kappa
Species Reactivity: Human, Mouse, and Rat. Others not known.
Positive Control: HepG2, 293T, K562 or RPMI-8226 Cells. Spleen from Hairy Cell Leukemia (HCL) patient.
Specificity: This antibody recognizes a protein of 35kDa, which is identified as tartrate-resistant acid phosphatase (TRAcP). It exists as two isoforms (5a and 5b). This antibody reacts with both the isoforms. The anti-TRAcP antibody labels the cells of Hairy Cell Leukemia (HCL) with a high degree of sensitivity and specificity. Other cells stained with this antibody are tissue macrophages and osteoclasts.