Napsin A; Clone EP205 (Concentrate)
Designation: Rabbit Monoclonal
Species Reactivity: Human. Others not tested.
Positive Control: Lung Adenocarcinoma or Renal Cell Carcinoma.
Specificity: Napsin A is expressed in the cytoplasm of 84.5% of primary lung adenocarcinomas (ADC) and 79% of renal cell carcinomas showing a granular staining pattern. It is also been observed in the glandular component of the adenosquamous cell carcinoma, while cells in the squamous component remain negative. Napsin A expression has also been observed in normal type II pneumocytes and some alveolar macrophages near the neoplasms, while no expression is seen in type I pneumocytes, bronchiolar epithelium, bronchial epithelium and stromal cells.