CD79a (B-Cell Marker); Clone JCB117 (Concentrate)
Immunogen: A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein.
Isotype: IgG1, kappa
Species Reactivity: Human. Others not known.
Positive Control: Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
Specificity: Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.