c-Myc Oncoprotein; Clone 9E10.3 (Concentrate)
Immunogen: A synthetic peptide, corresponding to aa 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from the C-terminus of human c-Myc, coupled to KLH.
Isotype: IgG1, kappa
Species Reactivity: Human. Does not react with Mouse, Rat, or Chicken. Others not tested.
Positive Control: HL-60 cells or breast carcinoma.
Specificity: This antibody recognizes a transcription factor of 64-67kDa, identified as c-Myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of the human c-Myc protein. This antibody shows no cross-reaction with v-Myc.