Macrophage Marker (Calgranulin A/B); Clone CAG/426 (Concentrate)
Immunogen: Recombinant human Calgranulin protein
Isotype: IgG1, kappa
Species Reactivity: Human, Baboon, Monkey, Cow, Pig, Goat, Horse, Cat, Dog, Rabbit, Guinea pig, Rat, and Mouse. Others not known.
Positive Control: Tonsil, lymph node, or spleen.
Specificity: Recognizes a 12-14kDa subunit of Calgranulin A/B (also known as S100A8/A9 or MRP-8/14); this protein is expressed by granulocytes, monocytes, and tissue macrophages. This antibody reacts with neutrophils, monocytes, macrophages, and squamous mucosal epithelia, and has been shown to be an important marker for identifying macrophages in tissue sections.