Cytokeratin 8; Clone KRT8/899 (Concentrate)
Immunogen: Cytoskeletal extract of Hep3B hepatocellular carcinoma cell line of human origin
Isotype: IgM, kappa
Species Reactivity: Human, Monkey and Rabbit. Others not known.
Positive Control: MCF-7 or A431 cells. Skin, Colon, lung or breast carcinoma.
Specificity: This antibody recognizes a 52.5kDa protein known as Cytokeratin 8. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19).