Bcl-6 (Follicular Lymphoma Marker); Clone IG191E/A8 (Concentrate)
Immunogen: Recombinant human bcl-6 protein
Isotype: IgG1, kappa
Species Reactivity: Human and Mouse. Others not known.
Positive Control: Raji or Ramos cells. Tonsil or Hodgkin's lymphoma.
Specificity: Recognizes a protein of 95kDa, which is identified as Bcl-6. The Reed-Sternberg cells of classical Hodgkin lymphoma are Bcl-6 negative whereas the large ("L&H") cells of NLPHL are Bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.