HSP60 (Heat Shock Protein 60); Clone LK1 (Concentrate)
Immunogen: Recombinant human HSP60 protein
Isotype: IgG1, kappa
Species Reactivity: Human, Mouse, Rat, Hamster, Sheep, Rabbit, Cow, Dog, Pig, Monkey, Chicken, Xenopus laevis, and Drosophila. Does not react with Bacteria, Helminths, and Spinach. Others not known.
Positive Control: HeLa or HepG2 cells. Breast carcinoma. Synovial biopsies from patients with juvenile chronic arthritis. Synovial lining layer is strongly positive for HSP60.
Specificity: This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60). Its epitope is localized between aa 383-447 of human HSP60. Clone LK1, unlike LK2, recognizes only the mammalian (not bacterial) HSP60 and is useful in distinguishing HSP60 from mammals and bacteria.