Fascin-1; Clone FSCN1/417 (Concentrate)
Immunogen: Recombinant human fascin protein
Isotype: IgG2a, kappa
Species Reactivity: Human. Others not known.
Positive Control: HeLa cells. Thymus, spleen or Hodgkin's lymphoma.
Specificity: Recognizes a protein of 55kDa, which is identified as fascin-1. This antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells.