CDX2 & Cytokeratin 7 Multiplex Cocktail; Clones EP25 & OV-TL12/30 (Ready-To-Use)
Species: Rabbit and Mouse
Designation: Cocktail of Rabbit and Mouse monoclonal antibodies to CDX-2 and CK7.
Immunogen: Rabbits were injected with a synthetic peptide corresponding to residues near the C-terminus of human CDX-2. BALB/C mice were injected with OTN11-ovarian cell carcinoma cell line.
Mol. Weight: Unknown
Clone: Clones EP25 and OV-TL12/30
Isotype: Rabbit IgG and Mouse IgG1, respectively.
Species Reactivity: Human
Positive Control: CDX-2: Colon for normal tissue and colon adenocarcinoma for abnormal tissue.
CK7: Carcinoma of ovary, lung, cervix, or breast.
Specificity: CDX-2 expression is restricted to nuclear staining in positive cells while CK7 expression is restricted to most glandular and transitional epithelia including lung, breast, bladder, and the female genital tract and their adenocarcinomas, but not in most gastrointestinal epithelium, prostate, hepatocyte, and squamous epithelium.