Estrogen Receptor; Clone 11D5 (Concentrate)
Isotype: IgG1, Kappa
Species Reactivity: Human
Positive Control: Breast Carcinoma.
Cellular Localization: Nuclei.
Specificity: This antibody is specific to estrogen receptor, which is associated with superior prognosis and a better response to endocrine therapy. The nuclei of the estrogen receptor positive cells stain very strongly with this antibody, without any staining in the cytoplasm. However, on cryostat sections a positive staining of estrogen receptor in the nucleus as well as cytoplasm can be seen. This antibody can be used for gel shift assay, immunoprecipitation, immunohistochemistry and western blotting.