CD31 / PECAM-1 (Endothelial Cell Marker); Clone JC/70A (Concentrate)
Immunogen: Membrane preparation of a spleen from a patient with hairy cell leukemia.
Isotype: IgG1, kappa
Species Reactivity: Human, Cynomolgus Monkey, and Rabbit. Others not known.
Positive Control: Tonsil, Angiosarcoma.
Specificity: Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. Anti-CD31 reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining.