MART-1 / Melan-A / MLANA (Melanoma Marker); Clone M2-7C10 (Concentrate)
Immunogen: Recombinant hMART-1 protein
Isotype: IgG2b, kappa
Species Reactivity: Human. Does not react with Mouse and Rat. Others not tested.
Positive Control: SK-MEL-13 and SK-MEL-19 Melanoma cell lines, Melanomas.
Specificity: This monoclonal antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T-cells 1) or Melan-A. This antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.