S100A7 / HID5 / Psoriasin (Proliferative Epithelial Cell Marker); Clone S100A7/542 (Concentrate)
Immunogen: Recombinant human S100A7 protein
Isotype: IgG1, kappa
Species Reactivity: Human. Others not known.
Positive Control: MCF-7 cells. Breast carcinoma.
Specificity: This antibody recognizes a protein of 11kDa, identified as S100A7. This protein is markedly over-expressed in the skin lesions of psoriatic patients. This protein is found to have elevated expression in abnormally differentiating primary keratinocytes and in various carcinomas, including ductal carcinoma in situ. It may serve as a marker of abnormally proliferative epithelia.