Renal Cell Carcinoma / gp200 (Carbonic Anhydrase IX); Clone 66.4.C2 (PN-15) (Concentrate)
Immunogen: Microsomal fraction of human renal cortical tissue homogenate
Clone: 66.4.C2 (PN-15)
Isotype: IgG2b, kappa
Species Reactivity: Human and Horse. Others not known.
Positive Control: Normal kidney or renal cell carcinoma.
Specificity: Recognizes a glycoprotein of ~200kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens.