MART-1 / Melan-A / MLANA (Melanoma Marker); Clone A103, M2-7C10 & M2-9E3 (Concentrate)
Immunogen: Recombinant hMART-1 protein (A103; M2-7C10; M2-9E3)
Clone: A103, M2-7C10 & M2-9E3
Isotype: IgG1 (A103); IgG2b (M2-7C10 & M2-9E3)
Species Reactivity: Human, Mouse, Rat and Dog. Others not tested.
Positive Control: SK-MEL-13 and SK-MEL-19 Melanoma cell lines, Melanomas.
Specificity: This monoclonal antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T-cells 1) or Melan-A. This antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.