p53 Tumor Suppressor Protein; Clone BP53-12 & DO-7 (Concentrate)
Immunogen: Recombinant human wild-type p53 protein (BP53-12); Recombinant human wild type p53 protein expressed in E. coli (DO-7).
Clone: BP53-12 & DO-7
Isotype: IgG2a (BP53-12); IgG2b, kappa (DO-7)
Species Reactivity: Human, Monkey, and Cow. Others not known.
Positive Control: MDA-MB-231 Cells. Breast or colon carcinoma.
Specificity: Recognizes a 53kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild type form of p53 under denaturing and non-denaturing conditions. Its epitope maps within the N-terminus (aa 20-25) of p53.