gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker); Clone HMB45 (Concentrate)
Immunogen: Extract of pigmented melanoma metastases from lymph nodes
Isotype: IgG1, kappa
Species Reactivity: Human. Does not react with Dog and Rat. Others not tested.
Positive Control: SK-MEL-28 cells or Melanoma.
Specificity: By immunohistochemistry, this antibody specifically recognizes a protein in melanocytes and melanomas. This antibody reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. This antibody also stains Angiomyolipoma (PEComa).